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🌍 Worldwide🩺 Medicine & Health📡 OpenAlex🕒 Updated November 2, 2026

Most-Cited Alzheimer's Disease Papers This Year (2026)

As of November 2, 2026, “Efficacy and safety of oral semaglutide 14 mg (flexible dose) in early-stage symptomatic Alzheimer's disease (evoke and evoke+): two phase 3, randomised, placebo-controlled trials” leads Most-Cited Alzheimer's Disease Papers This Year with 92 citations. “The TREM2 agonistic antibody AL002 in early Alzheimer’s disease: a phase 2 randomized trial” is second and “TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism” third. Biggest climber: “Engineering chimeric antigen receptor CD4 T cells for Alzheimer’s disease” (▲1).

🚫 No paid placement📡 Source: OpenAlex🕒 Updated November 2, 2026 ⓘ How we measure
Highlights: 🚀 Rising fastest: Engineering chimeric antigen receptor CD4 T cells for Alzheimer’s disease

Full ranking

2
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The TREM2 agonistic antibody AL002 in early Alzheimer’s disease: a phase 2 randomized trial ↗ •
Catherine Jane Mummery et al. · Nature Medicine · 2026-03-05
40 citationsCitations
3
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TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism ↗ •
Astrid Feiten et al. · Nature Communications · 2026-01-24
39 citationsCitations
4
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Targeting amyloid-β pathology by chimeric antigen receptor astrocyte (CAR-A) therapy ↗ •
Yun Chen et al. · Science · 2026-03-05
23 citationsCitations
5
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Efficient amyloid-β degradation in Alzheimer’s disease using SPYTACs ↗ •
Fei Teng et al. · Cell · 2026-03-04
23 citationsCitations
6
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The proportion of Alzheimer’s disease attributable to apolipoprotein E ↗ •
Dylan M. Williams et al. · npj Dementia · 2026-01-09
23 citationsCitations
7
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Low-Dose Lithium for Mild Cognitive Impairment ↗ •
Ariel G. Gildengers et al. · JAMA Neurology · 2026-03-02
19 citationsCitations
8
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Engineering chimeric antigen receptor CD4 T cells for Alzheimer’s disease ↗ ▲1🚀 Rising fastest
Pavle Boskovic et al. · Proceedings of the National Academy of Sciences · 2026-02-09
15 citationsCitations
9
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Effectiveness, safety, and biomarker dynamics of lecanemab in Chinese Alzheimer's disease population: a multicenter real‐world study ↗ ▲1
Wang Liao et al. · Alzheimer s & Dementia · 2026-03-01
14 citationsCitations

How this ranking works

Ranked by citation count (OpenAlex) among research papers published this year whose title or abstract matches this topic. Citations build up over time, so the newest papers rank lower. For information only, not medical advice.

Methodology →

SourceOpenAlex
SignalCitations
Last updatedNov 2, 2026, 4:27 PM UTC
Top 10Citations of papers published this year

Frequently asked questions

What is #1 in Most-Cited Alzheimer's Disease Papers This Year?

As of November 2, 2026, #1 is “Efficacy and safety of oral semaglutide 14 mg (flexible dose) in early-stage symptomatic Alzheimer's disease (evoke and evoke+): two phase 3, randomised, placebo-controlled trials”.

How is this ranking measured?

Ranked by citation count (OpenAlex) among research papers published this year whose title or abstract matches this topic. Citations build up over time, so the newest papers rank lower. For information only, not medical advice.

How often is this chart updated?

Data is re-collected automatically and every page shows its last update date.

Can a brand pay to appear in this ranking?

No. There are no paid placements and no commercial influence on rank.

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