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United States📈 Stocks📡 Yahoo Finance🕒 Updated November 2, 2026

Top Stock Losers Today (US) – 2026

As of November 2, 2026, “Krystal Biotech, Inc.” leads Top Stock Losers Today (US) with -14.81%. “Axsome Therapeutics, Inc.” is second and “Twist Bioscience Corporation” third.

🚫 No paid placement📡 Source: Yahoo Finance🕒 Updated November 2, 2026 ⓘ How we measure

Full ranking

1
📈
Krystal Biotech, Inc. ↗ 🏆 Leader
KRYS · $283.06
-14.81%Daily change
2
📈
Axsome Therapeutics, Inc. ↗
AXSM · $125.99
-12.77%Daily change
3
📈
Twist Bioscience Corporation ↗
TWST · $134.98
-11.65%Daily change
4
📈
Lumentum Holdings Inc. ↗
LITE · $743.08
-11.61%Daily change
5
📈
Iovance Biotherapeutics, Inc. ↗
IOVA · $7.70
-9.20%Daily change
6
📈
AbCellera Biologics Inc. ↗
ABCL · $11.19
-8.81%Daily change
7
📈
Cerebras Systems Inc. ↗
CBRS · $100.22
-8.21%Daily change
8
📈
Summit Therapeutics Inc. ↗
SMMT · $14.75
-7.99%Daily change
9
📈
Fastly, Inc. ↗
FSLY · $21.40
-7.42%Daily change
10
📈
Definium Therapeutics, Inc. ↗
DFTX · $33.48
-7.85%Daily change

How this ranking works

Ranked by percentage price drop in the current or latest US trading session. For information only, not investment advice.

Methodology →

SourceYahoo Finance
SignalDaily change
Last updatedNov 2, 2026, 4:27 PM UTC
Top 10Biggest daily percentage drops among US stocks

Frequently asked questions

What is #1 in Top Stock Losers Today (US)?

As of November 2, 2026, #1 is “Krystal Biotech, Inc.”.

How is this ranking measured?

Ranked by percentage price drop in the current or latest US trading session. For information only, not investment advice.

How often is this chart updated?

Data is re-collected automatically and every page shows its last update date.

Can a brand pay to appear in this ranking?

No. There are no paid placements and no commercial influence on rank.

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